Genetic polymorphisms in the CD14 gene are associated with monocyte activation and carotid intima-media thickness in HIV-infected patients on antiretroviral therapy.

Medicine (Baltimore) · 2016 · PMC4979844 · PMID 27495090

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

In HIV-infected patients, we found that the TT genotype was significantly associated with increased levels of sCD163 (median TT = 765.9 pg/mL vs CC/CT = 655.8 pg/mL; P = 0.049) and showed a trend of association with higher sCD14 ( P = 0.08).

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a trend toward significanceP = 0.08so close (0.05 < p ≤ 0.1)

Monocyte markers that were significantly associated with cIMT included the MFI for CD11b expression in total and CD14+ monocytes and HLA-DR expression in CD16+ monocytes, whereas HIV status showed only a trend toward significance ( P = 0.08).

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