The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.

Crit Care · 2016 · PMC4986344 · PMID 27527069

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did not reach statistical significanceno p-value reported

Prokinetic agents did not prevent feeding intolerance in patients without gastroparesis (RR 0.62, 95 % CI 0.31, 1.22, P = 0.16), but did reduce feeding intolerance in those with pre-existing gastroparesis (RR 0.70, 95 % CI 0.52, 0.96; P = 0.03), however, the interaction test did not reach statistical significance (Additional file 1 : Figure S8).

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