Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis.

J Exp Med · 2016 · PMC4986524 · PMID 27401344

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showed a trendno p-value reported

Interestingly, TGFβ in plasma showed a trend toward the highest levels in V617F;Ezh2 Δ/Δ mice, consistent with the role of TGFβ as a mediator of MF.

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