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Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

J Exp Med · 2016 · PMC4986526 · PMID 27401342

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4 A ); however, these differences did not reach statistical significance due to the small sample size ( IL10R and TYK2 ) or the variability of NEMO mutations on lymphocyte function.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.