However, as the number of NPM1 -mutated AML samples in our 84-sample CD34 + cohort was low ( n = 8), these differences did not reach statistical significance.
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Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.
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The sentences
The p-values of these comparisons were <0.001 (corrected for multiple testing), indicating that the differences between the overall expression of the 75-gene sets between CD34 − AML LSCs and CD34 + progenitor LSCs were highly significant.