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Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.

Hum Mol Genet · 2015 · PMC4986549 · PMID 25292197

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In contrast, the most effective dose of PTC124 treatment (10 μg/ml) appeared to increase RP2 mRNA levels compared with untreated R120X cells; however, this did not reach statistical significance (Fig. 3 A and B).

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