Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis.

Br J Pharmacol · 2015 · PMC4988470 · PMID 26375408

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did not reach statistical significanceP > 0.05actually significant

In addition, a trend towards decreased VA potency on this mutant was observed; however, this effect did not reach statistical significance (EC 50 = 84.1 ± 14.7 μM; P > 0.05; Figure 4 B).

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