Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy.

Oncotarget · 2016 · PMC4991408 · PMID 26910371

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did not reach statistical significanceno p-value reported

Although the differences did not reach statistical significance in a crude analysis of data for rectal cancer patients, our results nevertheless indicated that the efficacy of adding oxaliplatin to 5-FU was reversed at a specific age point.

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marginally significantno p-value reported

Modeling age as a continuous variable, there was a marginally significant interaction between age and the efficacy of oxaliplatin in terms of OS ( p for interaction = 0.082).

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