However, the up- and down-regulated gene sets overlapped in only 4 (up, Fisher test p -value: 0.036) and 2 (down, Fisher test p -value: 0.11) genes ( Figure 4 ), suggesting that in spite of the observed overlaps, which may be moderately significant for the up-regulated, but hardly significant for the down-regulated genes, naphthalene induces rather specific responses in the two tissues.
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"Upstream Analysis": An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data.
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The sentences
However, the up- and down-regulated gene sets overlapped in only 4 (up, Fisher test p -value: 0.036) and 2 (down, Fisher test p -value: 0.11) genes ( Figure 4 ), suggesting that in spite of the observed overlaps, which may be moderately significant for the up-regulated, but hardly significant for the down-regulated genes, naphthalene induces rather specific responses in the two tissues.