Evaluation of Biliary Calprotectin as a Biomarker in Primary Sclerosing Cholangitis.

5 , 21 , 22 In our study, patients with dominant bile duct stenoses at the ERC of sample acquisition with biliary calprotectin determination had shorter transplantation-free survival than patients without dominant stenoses, but the difference did not reach statistical significance.

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The difference in biliary calprotectin concentrations between the control and the PSC cohort was highly significant, although plasma CRP, ALP, and bilirubin concentrations were similar in the 2 groups, whereas plasma ALT and γGT concentrations were even higher in the control cohort as compared with the PSC cohort.

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