Although no significant difference was apparent between the histological scores of the FTY720 plus GPI 325‐339 and GPI 325‐339 alone groups, 3/5 mice in the GPI 325‐339 alone group (with a histological score of 2.0–2.5; Fig. 2 B), exhibited a moderate relapse (Fig. 2 A).
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Combination treatment with fingolimod and a pathogenic antigen prevents relapse of glucose-6-phosphate isomerase peptide-induced arthritis.
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