HOXA1 binds RBCK1/HOIL-1 and TRAF2 and modulates the TNF/NF-κB pathway in a transcription-independent manner.

Nucleic Acids Res · 2016 · PMC5009750 · PMID 27382069

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highly significantno p-value reported

In the present study we first establish a highly significant positive correlation between expression of HOXA1 and of members of the TNF/NF-κB signaling pathway in breast tumors.

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did not reach statistical significanceno p-value reported

sh-HOXA1 #4 and #5 also provoked a slight decrease in HOXA1 abundance and NF-κB reporter activity, although this did not reach statistical significance (Figure 2C ).

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