Critical appraisal of paclitaxel balloon angioplasty for femoral-popliteal arterial disease.

The analysis of the subgroup DCB + BMS (bailout stenting) vs DES showed a trend toward better clinical outcome in terms of TLR. 57 The meta-analysis of DES vs PTA + BMS (611 vs 307 patients) in infrapopliteal arteries resulted in reduced risk for intervention, restenosis, and amputations for the DES therapy, while there were no differences in terms of survival and RU. 58 In the Zilver PTX single arm study, DESs displayed good results in long de novo lesions, with PP rates of 77.6% and 74.8% and TLR rates of 14.6% and 19.5% after 12 months 59 and 24 months, 60 respectively.

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