Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men.

Treatment combinations containing kisspeptin (KP, NAL+KP, NKB+KP, NAL+NKB+KP) showed a large rise in LH, which was highly significant compared with vehicle ( P < .001) over time up to around 360 minutes, after which the values levelled off ( Figure 2 ).

also in 132,142 other papers

All kisspeptin-containing groups compared with vehicle showed a trend toward lower ApEn values, indicating more ordered pulses, but this reached the 1% significance level only for the NAL+NKB+KP group (NAL+NKB+KP, P < .001; KP, P = .02, NAL+KP, P = .02; NKB+KP, P = .04 vs vehicle).

also in 53,322 other papers