Cardiac action of the first G protein biased small molecule apelin agonist.

Biochem Pharmacol · 2016 · PMC5012889 · PMID 27475715

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showed a trendno p-value reported

CMF-019 similarly showed a trend to increase stroke volume and cardiac output (with a significant effect observed at 500 nmol) without a change in heart rate.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.