Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.

J Biol Chem · 2016 · PMC5016185 · PMID 27354281

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Retinoid analyses revealed that the LAMP1/RAB7-enriched fraction F1 showed a trend toward increased Res, whereas fraction F2 showed an ∼3-fold increased RE content in cells treated with Lalistat 2 compared with control cells (DMSO) ( Fig. 3 B ).

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