Isolating the Role of Bevacizumab in Elderly Patients With Previously Untreated Nonsquamous Non-Small Cell Lung Cancer: Secondary Analyses of the ECOG 4599 and PointBreak Trials.

Am J Clin Oncol · 2016 · PMC5016219 · PMID 25628268

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a nonsignificant trendno p-value reported

However, there was a nonsignificant trend in favor of the PC arm for postprogression OS among patients aged 75 years or above (median: 5.0 mo for PC+bevacizumab vs. 6.6 mo for PC; HR, 1.30; 95% CI, 0.77-2.30).

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did not reach statistical significanceno p-value reported

The incidence of grade 5 events in patients aged 75 years or above was 8% for those receiving bevacizumab with PC compared with 2% for those receiving chemotherapy alone, although the difference did not reach statistical significance.

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