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Pharmacological strategies to reduce exacerbation risk in COPD: a narrative review.

Respir Res · 2016 · PMC5018159 · PMID 27613392

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Moreover, although the annual rate of severe exacerbations did not reach statistical significance between the two treatment arms due to the low number of events, the time to first severe exacerbation was significantly longer with IND/GLY compared with SFC (19 % lower risk, p = 0.046).

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