an unfavorable trendp = 0.061
Compared with one tumor lesion, two lesions were significant unfavorable prognosticator of OS (HR, 3.148; 95% CI, 1.747–5.672; p < 0.001), three lesions also showed an unfavorable trend albeit without statistical significance (HR, 2.116; 95% CI, 0.967–4.633; p = 0.061).