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Anti-Inflammatory Effects of Hyperbaric Oxygenation during DSS-Induced Colitis in BALB/c Mice Include Changes in Gene Expression of <i>HIF-1α</i>, Proinflammatory Cytokines, and Antioxidative Enzymes.

Mediators Inflamm · 2016 · PMC5021505 · PMID 27656047

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There was also a tendency for upregulation of HIF-1α gene in MLN and spleens of the DSS group and its downregulation via HBO 2 in the DSS + HBO 2 group ( Figure 4(a) ); however, these changes did not reach statistical significance.

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