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MiR-424-5p participates in esophageal squamous cell carcinoma invasion and metastasis via SMAD7 pathway mediated EMT.

Diagn Pathol · 2016 · PMC5024440 · PMID 27628042

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a negative trendno p-value reported
So in ESCC tissues, we came to the conclusion that down-regulated miR-424-5p had a negative trend with the invasion and metastasis of ESCC.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.