The Contribution of Mosaic Variants to Autism Spectrum Disorder.

PLoS Genet · 2016 · PMC5024993 · PMID 27632392

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0.1200

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did not reach statistical significancep = 0.12not close (p > 0.1)

In addition, we observed enrichment of mosaic missense and LGD mutations in probands and siblings in genes involved in embryonic development (18 observed versus 12.6 expected for probands; 9 observed versus 6.7 expected for siblings), however this enrichment did not reach statistical significance (p = 0.12 for probands; p = 0.30 for siblings).

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