Immunofluorescence staining indicated that mediastinal FALCs of naive Il1rl1 −/− mice are smaller than their BALB/c counterparts, flow cytometric analysis of digested pericardial FALCs showed a trend for fewer cells in the mediastinal adipose but this did not reach significance ( Fig. 3b ).
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Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation.
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