Patient-centered care interventions for the management of alcohol use disorders: a systematic review of randomized controlled trials.

The remaining study by Gual et al reported a baseline to 6-month difference of −5.0 g/day favoring the PCC group, but it did not reach statistical significance (95% CI −10.6 to 0.7; P =0.08). 65 Hazardous and heavy drinking The four studies assessing this outcome (Heinala et al, 2001, Karhuvaara et al, 2007, Mann et al, 2013, and Gual et al, 2013) reported statistically significant differences in heavy drinking favoring the PCC groups. 64 – 67 The 6-month

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