Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials.

PLoS One · 2016 · PMC5029878 · PMID 27649492

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp<0.001actually significant

The PUL scale showed highly significant loss of function at 12 months (p<0.001), with a mean drop in score of 9.2 (95% CI -11.9; -6.4) out of 74; this numerical result was predominantly driven by the loss of function in the shoulder domain.

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failed to reach statistical significanceno p-value reported

All other evaluations, including spirometry and muscle strength measurement with myometry, failed to reach statistical significance in our cohort.

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