Still, BCP-ALL of presumed fetal origin showed a trend to less frequently use long D h genes than the other BCP-ALL ( Supplementary Figs 5a and 6a ), and the IgH-CDR3 length was shorter in BCP-ALL of presumed fetal origin.
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Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin.
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