a strong trendp = 0.064
Those treated with ZA had a 23% reduction in the risk of disease recurrence (absolute reduction of 3.4%; hazard ratio (HR) 0.77 (95% CI 0.60–0.99), p = 0.042) and a strong trend towards improved survival (HR 0.66 (95% CI 0.43–1.02), p = 0.064).