Citation bias favoring positive clinical trials of thrombolytics for acute ischemic stroke: a cross-sectional analysis.

However, rates of intracranial hemorrhage, symptomatic intracranial hemorrhage, and fatal intracranial hemorrhage were significantly higher in the intervention group; there was a strong trend towards increased overall 90-day mortality in the intervention group ( p = 0.09); and in their conclusion the study authors describe their results as “negative” [ 18 ].

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