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Introducing candesartan 32 mg plus hydrochlorothiazide 25 mg in previously untreated patients with severe essential hypertension.

Pragmat Obs Res · 2011 · PMC5045001 · PMID 27774009

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a clear trendno p-value reported
The mean ASAT and ALAT increases over time were accompanied by a median representing a mild decrease so that a clear trend did not become obvious.

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