Interestingly, this locus was approaching significance in association with decreased sensitivities to PPQ, a partner drug in the ACT mostly used at the China-Myanmar border ( Fig. 3 , Supplementary Fig.
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Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border.
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Pairwise comparison between the 10 drugs by Spearman’s rho analysis revealed highly significant, positive, correlations among the IC 50 s of DHA, AS and AM.