The body weight gain of db/+ mice on high fructose diet showed a trend of reduction in body weight of mice treated with PTM at 100 mpk, while food intake was not affected during the 29-day treatment of PTM in drinking water ( Fig 3D and 3E ).
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The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.
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