For example, in 2016 African American (AA) breast cancer patients and 2745 controls, 36 of 47 (67 %) EA breast cancer risk SNPs had ORs in AA in the same direction, and seven (15 %) had nominally significant P values [ 36 ].
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The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance.
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