A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis.

Arthritis Res Ther · 2016 · PMC5050569 · PMID 27716427

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0.2000

closest p · 4.0× alpha

0.2000

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did not reach statistical significancep ≥ 0.2not close (p > 0.1)

Although differences between AA + AG and GG genotypes did not reach statistical significance ( p ≥ 0.2), all five clinical criteria showed the same tendency associated with more severe disease only in GG genotype carriers (Fig. 2a ).

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