Pro-inflammatory cytokines and chemokines exhibited a sexually dimorphic profile, wherein there was a highly significant increase in expression of IL-6 mRNA in male mice and a trend of increase noted in female mice.
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Sexual Dimorphism in Alcohol Induced Adipose Inflammation Relates to Liver Injury.
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TNFα mRNA levels were unchanged in male adipose tissue but female adipose tissue showed a trend towards increased expression ( Fig 3A ).