Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells.

Oncotarget · 2016 · PMC5053657 · PMID 27036042

Europe PMC DOI

hedged sentences

0.0020

closest p · 0.0× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.002actually significant

This relation became highly significant when removing two extremely ATO-resistant lung cancer cell lines from the regression analysis (r 2 = 0.82, p < 0.002) suggesting that NSCLC cell lines might be characterized by additional, tissue type-specific resistance mechanisms against ATO.

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showed a trendp = 0.1so close (0.05 < p ≤ 0.1)

In addition, intrinsic Met expression showed a trend to inversely correlate with ATO sensitivity in the entire cell line panel (r 2 = 0.3, p = 0.1).

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