Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment.

Oncotarget · 2016 · PMC5053693 · PMID 27034165

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Our data showed a trend of up-regulation of α-internexin in hippocampus in TRPC1 −/− mice and EE could significantly suppress the expression of α-internexin, indicating an involvement of α-internexin in memory impairment in TRPC1 −/− mice and the protective effects of EE on memory.

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