Oligodendrocyte Development in the Absence of Their Target Axons In Vivo.

In the posterior spinal cord, the rate of occurrence of OPC mitoses was significantly reduced in mutants (0.9±1.1 vs 0.3±0.5 mitoses/12-hour in WT vs mutants, P = 0.029 in t-test, Fig 8D ), while in the anterior spinal cord a similar trend did not reach statistical significance (1.8±2 vs 0.7±1.4 mitoses/12-hour in WT vs mutants, P = 0.107 in t-test, Fig 8E ).

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