Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer.

World J Clin Oncol · 2016 · PMC5056326 · PMID 27777877

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showed a trendno p-value reported

A recent study of patients with metastatic CRC harboring wild-type KRAS showed a trend towards improved PFS in patients with wild-type PIK3CA compared to PI3KCA -mutant patients who received cetuximab either as a monotherapy or in combination with chemotherapy ( P = 0.06)[ 68 ].

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