Grey and White Matter Clinico-Anatomical Correlates of Disinhibition in Neurodegenerative Disease.

Correlations with the Frontal Behavioural Inventory In the linear regression model with the FBI 12-22 of the combined patient cohort as the dependent variable, a statistically highly significant effect was seen for the right UF (adjusted R 2 = 0.44, unstandardized B = -116 [95% CI -182, -50], p = 0.002), left UF (adjusted R 2 = 0.319, B = -98 [95% CI -167, -29], p = 0.008), the right aCi (adjusted R 2 = 0.23, B = -56 [95% CI -105, -7.6], p = 0.026) and forceps minor (adjusted R 2 = 0.26, B = -77, [95% CI -139, -14], p = 0.019) ( Fig 4 ).

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Although median total error score was higher in the bvFTD than the PSP group, this did not reach statistical significance ( p = 0.055).

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