A Review of the External Validity of Clinical Trials with Beta-Blockers in Heart Failure.

Clin Med Insights Cardiol · 2016 · PMC5063839 · PMID 27773994

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

80 In the COMET study, which compared carvedilol and metoprolol, the diabetics, who comprised 24% of the patients, did not reach statistical significance. 79 , 86 Published RCTs have not conclusively addressed the question of whether a BB class is superior in CHF with comorbid DM, and this remains an area for Phase IV trials.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.