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Current debate in the oncologic management of rectal cancer.

World J Gastrointest Oncol · 2016 · PMC5064049 · PMID 27795811

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The preliminary results from this study showed pathologic complete response of 25% in those treated with the upfront modified FOLFOX-6 compared to 18% in those who proceeded to surgery directly, but this result did not reach statistical significance[ 22 ].

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