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In vitro impact of pegvisomant on growth hormone-secreting pituitary adenoma cells.

Endocr Relat Cancer · 2016 · PMC5064756 · PMID 27267119

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Although the analysis did not reach statistical significance, probably due to the low number of tumors, we observed a trend for a positive correlation between the expression level of GHR mRNA and the percentage of maximal inhibition of GH secretion under PEG 1μg/mL ( r =0.68, P =0.07, Fig. 3C ).

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