A scalability study of phylogenetic network inference methods using empirical datasets and simulations involving a single reticulation.

Three exceptions to this observation were noted: (1) MP was consistently less accurate than the other methods but otherwise did not show a clear trend of change as dataset size increased, (2) MLE, MLE-length, MPL, and SNaQ’s topological accuracy decreased as dataset size increased from 6 to 7 taxa, and (3) SNaQ’s topological accuracy decreased as dataset size increased from 20 to 25 taxa.

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