marginally non-significantP =0.052
When HCC cases diagnosed during the first year were excluded, the risk reduction became marginally non-significant ( P =0.052), but a type II error related to the early trial termination could not be excluded.
When HCC cases diagnosed during the first year were excluded, the risk reduction became marginally non-significant ( P =0.052), but a type II error related to the early trial termination could not be excluded.
The reduction of the HCC incidence resulted mainly from the two Oriental studies, while the 4.8% reduction of HCC incidence in the five European studies did not reach statistical significance.