Although similar rhythmicity was visible in cells of trained lean (TL) and type 2 diabetic patients (T2D), differences in time did not reach statistical significance for PER2 (p = 0.13 and p = 0.12 in TL and T2D respectively) whereas one-way ANOVA revealed significant differences for all four donor groups for PER3.
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Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.
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