Barely Significant
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Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.

PLoS One · 2016 · PMC5072561 · PMID 27764152

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quite significantno p-value reported
If one goes to 1 μM, non-specific dimers become quite significant (25.6%), but this is accompanied by a large number of non-specific trimers (21.4%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.