Pentoxifylline I ( P = 0.054) also tended to have a negative influence on flap survival, but this effect failed to reach statistical significance.
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Impact of different antithrombotics on the microcirculation and viability of perforator-based ischaemic skin flaps in a small animal model.
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The sentences
Since these conditions do not closely resemble the clinical situation, it is likely that, although the influence of antithrombotics may not be significant in routine cases with low thrombogenic risks, their effect may be greater under thrombogenic conditions 24 .