Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice.

On day 4 after injury, mRNA expression of Myog and Myh3 was significantly lower in regenerating muscles from Pax7 CE/+ ;Klf5 flox/flox mice than control mice; Pax7 and Myod1 levels also tended to be reduced, but the differences did not reach statistical significance ( Figure 2A ).

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