A Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models.

PLoS One · 2016 · PMC5082879 · PMID 27788148

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0.0700

closest p · 1.4× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

We also found that amplification of PAK4 and RGS19 tended to be mutually exclusive, although this trend did not reach statistical significance, ( P = 0.07, Fisher’s exact test, Fig 6C ), whereas amplification of RYR1 and PAK4 tended to co-occur, an association that did reach statistical significance ( P <0.001, Fisher’s exact test, Fig 6D ).

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did not quite reach significanceP = 0.08so close (0.05 < p ≤ 0.1)

However, the original study that analyzed GSE17308 showed that the difference did not quite reach significance ( P = 0.08, Kruskal-Wallist test) and had no observable effect on gene expression profiles in unsupervised clustering analysis or in supervised ANOVA analyses [ 9 ].

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