MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

If only the highest titer sample in each patient is considered, the median titer in group I was 1:1280 (range 160–20480; N = 50); maximum titres were higher in patients with a history of myelitis (median 1:2560, range 160-20480; N =7) or a history of both myelitis and ON (1:1280; range 160-10240; N =22) at last follow-up than in patients with a history of ON but no myelitis at last follow-up (1:640; range 160-20480; N =21), but the difference did not reach statistical significance.

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